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OCR: The illustration shows how DNA is cloned in a plasmid vector. First, the target DNA and vector DNA are cut with the same restriction enzyme. Next, the target DNA fragments and vector DNA are annealed and sealed with ligase, producing circular recombinant DNA molecules that each contain a fragment of target DNA inserted into the vector. These molecules are then introduced into bacterial cells for re plication. Transformed cells are selected by antibiotic resistance. Each resulting bacterial colony, called a clone, will contain many replicates of a different segment of target DNA. A large collection of such clones, which together include all the fragments present in the target DNA, is called a library.